Yini ukhilimu weGelmicin?
Ukubonakaliswa kokucindezelwa kwe-adrenal ezinganeni kufaka phakathi ukubambezeleka kokukhula okulinganayo, ukungabi bikho kwesisindo, amazinga aphansi e-plasma cortisol, kanye nokuntuleka kokuphendula ekugqugquzelweni kwe-ACTH. Ukuphepha kokusebenzisa ama-topical corticosteroids ngesikhathi sokukhulelwa akukatholakali, ngakho-ke kufanele kusetshenziswe kuphela kulezi zimo uma inzuzo engaba khona ibeka engcupheni engaba khona enganeni. Izidakamizwa zalolu hlobo akufanele zisetshenziswe kakhulu ngamanani amakhulu noma isikhathi eside ezigulini ezikhulelwe. Njengoba kungazange kunqunywe ukuthi ngabe ukuphathwa ngezihloko kwama-corticosteroids kungaholela ekumunweni okwanele kwe-systemic ukukhiqiza amanani atholakala obisini lwebele, kufanele kwenziwe isinqumo sokuthi kuyekwe ukuncelisa noma umuthi, kucatshangelwa ukubaluleka komuthi wokuncelisa. . Ukusetshenziswa kwezingane: Iziguli ezinganeni zingabanjwa kakhulu ukucindezelwa kwe-axis ye-hypothalamic-pituitary-adrenal (HPA) ekhiqizwa yi-topical corticosteroids kanye nemiphumela ye-corticosteroids engaphandle. Lokhu kungenxa yokuthi ezinganeni isilinganiso esiphakathi kwendawo yesikhumba nesisindo somzimba siphakeme, futhi ngenxa yalokho ukumuncwa kuphakeme. Izigameko zokucindezelwa kwe-axis ye-HPA, i-Cushing's syndrome, ukubambezeleka kokukhula okulinganayo, ukungabi bikho kwesisindo somzimba, kanye nomfutho wegazi ophakeme ngokwedlulele kubikwe ezinganeni ezithola i-topical corticosteroids. Ukubonakaliswa kokucindezelwa kwe-adrenal ezinganeni kufaka phakathi amazinga aphansi e-plasma cortisol nokuntuleka kokuphendula ekugqugquzelweni kwe-ACTH. Ukubonakaliswa kwe-hypertension okungasebenzi kahle kufaka phakathi ikhanda kanye ne-papilledema yamazwe amabili. Lo mkhiqizo akufanele usetshenziswe ngokugqoka okukhona. Uma ukucasuka noma ukuzwela kukhula, ukwelashwa kufanele kumiswe futhi kuthathwe izinyathelo ezifanele. Lapho kukhona ukutheleleka kwamagciwane, i-ejenti elwa namagciwane efanelekayo kufanele isetshenziswe ngokuvumelana. Uma kungekho mpendulo ku-GELMICIN Cream, izifundo ze-microbiological kufanele ziphindwe ukuqinisekisa ukuxilongwa nokuqeda izinsolo zamanye ama-pathogen ngaphambi kokwenza olunye uhlobo lokwelashwa okulwa nokubola. Ngokusetshenziswa kwama-topical corticosteroids, noma yimiphi imiphumela emibi ebikwe ngokusetshenziswa kwe-systemic corticosteroids ingenzeka, kufaka phakathi ukucindezelwa kwe-adrenal, ukubonakaliswa kwe-Cushing's syndrome, hyperglycemia kanye ne-glycosuria. Ukufakwa kwesistimu kwama-topical corticosteroids kungabalulekile uma usebenzisa ama-corticosteroid agents anamandla, ngokusetshenziswa isikhathi eside, noma lapho welapha izindawo ezinkulu zomzimba. Ngakho-ke, iziguli ezithola amanani amakhulu ama-corticosteroids Uma kwenzeka ukucindezelwa kwe-HPA axis kwenzeka, umuthi kufanele uhoxiswe kancane kancane, imvamisa yokusetshenziswa incishiswe, noma ithathelwe indawo yi-ejenti enamandla kakhulu ye-corticosteroid. Ukubuyiselwa komsebenzi we-HPA axis kuvame ukushesha futhi kuqede ngemuva kokuyeka ukwelashwa. Kwezinye izimo, izimpawu nezimpawu zokuhoxa kwe-corticosteroid zingabonakala, okuzodinga ukwelashwa okuhambisanayo kwe-corticosteroid. I-Clotrimazole i-ejenti ebanzi yokulwa nezifo esetshenziswa ekwelapheni ukutheleleka kwesikhumba okubangelwa yizinhlobo ezahlukahlukene ze-pathogenic dermatophytes, imvubelo neMalassezia furfur. Isenzo esikhulu se-clotrimazole siphikisana nokwehlukanisa nokukhula kwezinto eziphilayo. Ngaphezu kwalokho, kubonakala sengathi i-clotrimazole isebenza kulwelwesi lweseli lwefungus, okwenza okuqukethwe kweseli kuphunyuke. Ngemuva kokuphathwa ngezihloko kwesikhumba, i-clotrimazole cishe ayingeni. Ngisho ngamahora ayisithupha ngemuva kokufakwa kokhilimu we-1% we-clotrimazole noma isisombululo esikhunjeni esigxilile noma esivuthayo, ukuminyana kwe-clotrimazole kuyehluka kusuka ku-100 mg / ml ku-stratum corneum kuye ku-0.5 kuye ku-1 mg / ml ku-stratum reticularis. Kanye no-0.1 mg / ml ku-dermis. Ayikho inani elinganisekayo le-radioactivity etholakalayo (<0.001 mg/ml) en el suero 48 horas después de la aplicación de 0.5 ml de solución o 0.8 g de crema bajo una curación oclusiva. Emuntwini, cishe ama-25% we-clotrimazole elawulwa ngomlomo akhishwa emchameni, kanti okusele kukhishwa endle zingakapheli izinsuku eziyisithupha kungenisiwe. I-Betamethasone dipropionate iyi-corticosteroid esebenzayo ekwelapheni ama-dermatoses aphendula ekwelashweni kwe-corticosteroid ngenxa yesenzo sayo sokulwa nokuvuvukala, i-antipruritic kanye ne-vasoconstrictive. Njengoba kuyisici se-corticosteroids, i-betamethasone dipropionate imuncwa esikhunjeni, iboshwe ngokusobala kumaphrotheni e-plasma, ihlanganiswa namasayithi we-hepatic ne-extrahepatic, inikeze izinto ezingasebenzi, futhi ikhishwe ngokuphelele ngaphakathi kwamahora angama-72 ngezinso. Izimpawu: Ukusetshenziswa ngokweqile noma isikhathi eside kwama-topical corticosteroids kungacindezela ukusebenza kwe-pituitary-adrenal, kubangele ukungasebenzi kahle kwe-adrenal yesibili futhi kuveze ukubonakaliswa kwe-hypercorticism, kufaka phakathi isifo sikaCushing. Ukwelashwa: Ukwelashwa okuyizimpawu kukhonjisiwe. Izimpawu ezinzima ze-hypercorticoid zivame ukubuyiselwa emuva. Ukungalingani kwe-Electrolyte kufanele kubhekwane nakho, uma kunesidingo. Uma kwenzeka kunobuthi obungapheli, kunconywa ukuhoxiswa kancane kancane kwe-corticosteroid. Gcina endaweni epholile. Gcina lapho izingane zingafinyeleli khona. Ukuthenga kwakho kudinga incwadi kadokotela. Izincwadi ezikhethekile zodokotela. UKUBHALISWA KWE-GELMICIN: Reg. UNúm. 523M97, SSA IGELMICIN IGAMA ELIVAMILE: Ukuthola inzuzo enhle kakhulu, kubalulekile ukuthola umthamo ngamunye ohleliwe walo muthi njengoba uyalelwe. Uma ukhohlwa ukuthatha umthamo wakho, xhumana nodokotela wakho noma usokhemisi khona manjalo ukusungula uhlelo olusha lokulinganisa. Ungawuphindi kabili umthamo ukuze ubambe. Uma umuntu eyeqile futhi enezimpawu ezinzima njengokuquleka noma ukuphefumula okuncane, shayela ku-911. Ngaphandle kwalokho, shayela isikhungo sokulawula ubuthi ngokushesha. Izakhamizi zase-United States zingashayela isikhungo sendawo sabo sokulawula ubuthi ku 1-800-222-1222 . Izakhamizi zaseCanada zingashayela isikhungo esilawula ubuthi esifundazweni. Izimpawu zokudlula ngokweqile zingafaka: ukuquleka. Ungahlanganyeli lo muthi nabanye. Ukuhlolwa kwelabhorethri kanye / noma kwezokwelapha (njengokubala okuphelele kwegazi, ukuhlolwa kwezinso) kufanele kwenziwe ngenkathi usebenzisa lo muthi. Gcina konke ukuqokwa kwezokwelapha kanye nelabhorethri. Thintana nemiyalo yomkhiqizo kanye nosokhemisi wakho ngemininingwane yokugcina. Gcina yonke imishanguzo ezingafinyeleli ezinganeni nasezilwaneni ezifuywayo, ungafaki imishanguzo ethoyilethi noma uyithululele edreyini ngaphandle uma uyaliwe. Lahla kahle lo mkhiqizo uma usuphelelwe yisikhathi noma ungasadingeki. Thintana nosokhemisi wakho noma inkampani yangakini yokulahla imfucuza. Ukuzikhulula: Imininingwane yezidakamizwa equkethwe lapha ingashintsha futhi ayihloselwe ukumboza konke ukusetshenziswa okungaba khona, imiyalelo, izixwayiso, izexwayiso, ukuxhumana kwezidakamizwa, ukungezwani komzimba, noma imiphumela emibi. Ukungabikho kwezixwayiso noma olunye ulwazi lomuthi othile akubonisi ukuthi inhlanganisela yezidakamizwa noma yezidakamizwa iphephile, iyasebenza, noma ilungele zonke iziguli noma konke ukusetshenziswa okuthile. Izinkomba: https://es.wikipedia.org/wiki/Gentamicina Okuqukethwe
Ukubonakaliswa kwe-hypertension okungasebenzi kahle kufaka phakathi ikhanda kanye ne-papilledema yamazwe amabili.UKUKHULELWA NOKUGONYWA
IZINYATHELO ZEGELMICIN
Ama-topicals anamandla, asetshenziswa endaweni enkulu yomzimba, kufanele ahlolwe ngezikhathi ezithile ukuthola ubufakazi bokucindezelwa kwe-axis ye-hypothalamic-pituitary-adrenal (HPA).IPHEMACOKINETIC GELMICIN
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I-GELMICIN YOKUPHILA
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IBetamethasone neClotrimazole.Umthamo - Uma uphuthelwa umthamo
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